Exposure of anti-infective drugs and the dynamic changes of the gut microbiota during gastrointestinal mucositis in autologous stem cell transplant patients: a pilot study

HIGHLIGHTS

• who: Anne-Grete Mu00e4rtson from the A prospective, observational pilot study was performed at the Department of Hematology, University Medical Center Groningen (UMCG), Groningen, the NetherlandsPatients aged u2265 , years undergoing HSCT and receiving anti-infective prophylaxis (ciprofloxacin, fluconazole, or valacyclovir) as routine clinical care were eligible for inclusion. Patients deemed unsuitable to participate at inclusion (e_g, critical illness resulting in severely reduced life expectancy) as judged by the attending physician were not included in the study. Written informed consent was obtained from each patient. The study was evaluated by the Medical Ethics Committee of UMCG and considered . . .
  

   

  

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