Expression of a catalytically inactive mutant form of glutathione peroxidase 4 (gpx4) confers a dominant-negative effect in male fertility*

HIGHLIGHTS

• who: Irina Ingold from the (UNIVERSITY) have published the article: Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility*, in the Journal: (JOURNAL) of April/24,/2015

SUMMARY

Generation of Transgenic Mice Expressing the Serine Variant of Gpx4 (Gpx4_U46S)-For the generation of the mutant mice expressing the serine variant of Gpx4 (in the following referred to as Gpx4_U46S), the two vectors pPNT4.8 and pPNT4.10 were used. Germ line transmission was confirmed by PCR in six offspring. Out of 25 . . .

 



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