Expression of the relaxin family peptide 4 receptor by enterochromaffin cells of the mouse large intestine

HIGHLIGHTS

  • who: Ada Koo from the Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia have published the article: Expression of the relaxin family peptide 4 receptor by enterochromaffin cells of the mouse large intestine, in the Journal: (JOURNAL)
  • what: The authors have utilised an Rxfp4-dependent reporter mouse (Lewis et_al 2021) to investigate which of the types of 5-HT-containing EEC express Rxfp4 throughout the mouse colon, and the authors have also investigated whether the stimulation of colonic propulsion using an RXFP4-specific agonist is inhibited by a 5-HT3 receptor blocker . . .

     

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