HIGHLIGHTS
- who: Emre Balta from the Tianjin University, China have published the research work: Expression of TRX1 optimizes the antitumor functions of human CAR T cells and confers resistance to a pro-oxidative tumor microenvironment, in the Journal: (JOURNAL)
- what: In light of the findings on the importance of TRX1 in T_cells and published data on the hypo-responsiveness of T_cells under pro-oxidative conditions , the authors aimed to improve T_cell resistance to the pro-oxidative solid TME and thereby increase their efficacy against and longevity in solid tumors. The authors investigated the molecular and functional . . .
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