HIGHLIGHTS
- who: Influenza and collaborators from the InstitutGriffith University have published the research work: Extended AbstractA Novel Series of Sialic Acid-Based, in the Journal: (JOURNAL) of 17/05/2019
SUMMARY
Successful inhibition of the viral neuraminidase hinders the release of virion progeny from the infected host cell and significantly reduces further virus spread. One of the designed sialosyl α-sulfonate derivatives is a nanomolar inhibitor2 in a cell-based influenza virus replication assay and has comparable activity to that of anti-influenza drugs zanamivir and the active form of oseltamivir, oseltamivir carboxylate. The authors . . .
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