HIGHLIGHTS
- who: Brenna Conin et al. from the Center for Interdisciplinary Research in Biology (CIRB), Collu00e9ge de France, CNRS, INSERM, Universitu00e9 PSL have published the paper: Extended sister-chromosome catenation leads to massive reorganization of the E. coli genome, in the Journal: (JOURNAL) of June/01,/2021
- what: The authors investigated chromosome folding in cells with altered decatenation activities. The authors propose that the large-scale conformational changes observed under these conditions reveal defective decatenation attempts involving the terminus area. The authors investigate, using Hi-C, the effect of different topoisomerases on E. coli chromosome conformation . . .
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