Extensive patient-to-patient single nucleus transcriptome heterogeneity in pheochromocytomas and paragangliomas

HIGHLIGHTS

• who: Peter Brazda from the National Institute of Health Sciences (NIHS), Japan University of Florida, United States have published the research work: Extensive patient-to-patient single nucleus transcriptome heterogeneity in pheochromocytomas and paragangliomas, in the Journal: (JOURNAL)
• what: The authors exploited recent advances in single-nuclei RNA-seq to compare the gene_expression landscapes of PCPG with SDHB an d RET germ line mutations, explore transcriptional heterogeneity, and gain insight into the molecular basis of their different prognoses. The authors aimed to determine the transcriptional programs that are active across tumor cells and then identify . . .
  

   

  

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