Extracellular 5′-methylthioadenosine inhibits intracellular symmetric dimethylarginine protein methylation of fuse-binding proteins

HIGHLIGHTS

  • who: Baiqing Tang from the (UNIVERSITY) have published the Article: Extracellular 5u2032-methylthioadenosine inhibits intracellular symmetric dimethylarginine protein methylation of FUSE-binding proteins, in the Journal: (JOURNAL) of May/23,/2022
  • what: Using a transcription reporter construct containing the far upstream element site, the authors demonstrate that MTA addition can reduce transcription, suggesting that the reduction in FUBP1 and FUBP3 sDMAylation has functional consequences.
  • how: The authors examined the level of sDMAylation of the proteins by performing IP experiments.
  • future: Studies will need to be performed to see how universal is . . .

     

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