Extracellular camp-adenosine pathway signaling: a potential therapeutic target in chronic inflammatory airway diseases

HIGHLIGHTS

  • who: Enio Setsuo Arakaki Pacini from the Federal University of Rio de Janeiro, Brazil have published the research: Extracellular cAMP-Adenosine Pathway Signaling: A Potential Therapeutic Target in Chronic Inflammatory Airway Diseases, in the Journal: (JOURNAL)
  • future: The discovery of an extracellular enzymatic system in airways that converts cAMP into adenosine and can affect the primary cellular response initiated by intracellular cAMP opened new perspectives on how to envision the role of cAMP in airway physiology highlighting the importance of the mechanisms of cAMP extrusion and its function as an alternative source of extracellular adenosine . . .

     

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