Extracellular signal-regulated kinase (erk) phosphorylates histone deacetylase 6 (hdac6) at serine 1035 to stimulate cell migration*

HIGHLIGHTS

  • who: Kendra A. Williams from the (UNIVERSITY) have published the paper: Extracellular Signal-regulated Kinase (ERK) Phosphorylates Histone Deacetylase 6 (HDAC6) at Serine 1035 to Stimulate Cell Migration*, in the Journal: (JOURNAL) of November/15,/2013
  • what: The authors have demonstrated that HDAC6 is a novel ERK substrate.
  • how: The results showed that Ser-1035 was a major phosphorylation site for ERK1 as evidenced by the disappearance of the phosphorylation signal when this site was mutated VOLUME 288.
  • future: Future studies employing Thr-1031 phosphorylation or 33168 JOURNAL OF BIOLOGICAL CHEMISTRY . . .

     

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