Extracellular vesicles derived from antigen-presenting cells pulsed with foot and mouth virus vaccine-antigens act as carriers of viral proteins and stimulate b cell response

HIGHLIGHTS

  • What: The experiments demonstrated that FMDVi proteins/ peptides were detected in EVs-FMDVi. This work demonstrated that EVs-FMDVi induce the proliferation of previously primed T_cells but not naïve T_cells. The authors demonstrate that EVs derived from APC participate in B cell activation and could play an important role in the generation of the humoral response against FMDV.
  • Who: Nils Ludwig and collaborators from the University Hospital Regensburg, Germany have published the Article: Extracellular vesicles derived from antigen-presenting cells pulsed with foot and mouth virus vaccine-antigens act as carriers of viral proteins . . .

     

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