Extreme positive epistasis for fitness in monosomic yeast strains

HIGHLIGHTS

• What: The authors suspended attempts to derive M12, especially since, as the authors show below, its predicted burden of haploinsufficiency was well within the range covered by other chromosomes. The authors aimed at finding any distinct and functionally interpretable patterns of adjustments that could explain why the monosomics performed better than expected.
• Who: Evolutionary Biology and colleagues from the Institute of Environmental Sciences, Jagiellonian University, Cracow, Poland have published the research work: Epistasis supports viability under extensive gene- dose insufficiency following chromosome loss, in the Journal: (JOURNAL)
• How: The cultures were tested for . . .
  

   

  

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