Ezh2 and kdm6b expressions are associated with specific epigenetic signatures during emt in non small cell lung carcinomas

HIGHLIGHTS

  • who: Camille Lachat and colleagues from the Laboratory of Experimental Pathology, GIGA-Cancer, University of Liege, Liege, Université Rennes1, Rennes, France have published the research work: EZH2 and KDM6B Expressions Are Associated with Specific Epigenetic Signatures during EMT in Non Small Cell Lung Carcinomas, in the Journal: (JOURNAL)
  • what: The authors evaluated the function of these two enzymes using an EMT-inducible model the lung cancer A549 cell line.
  • how: The authors next decided to clarify the function of these enzymes during EMT using specific inhibitors of EZH2 and KDM6B (EZH2i GSK343 and . . .

     

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