HIGHLIGHTS
- who: Han-Rong Weng and collaborators from the Department of Basic Sciences, California Northstate University College of Medicine, Elk Grove, CA, USA have published the paper: EZH2 Methyltransferase Regulates Neuroinflammation and Neuropathic Pain, in the Journal: Cells 2023, 12, 1058. of /2023/
- what: Collectively, this study demonstrated that EZH2 induces neuroinflammation by suppressing miR-146a-5p gene_expression, resulting in increased HIF-1u03b1 expression and neuroinflammatory responses.
SUMMARY
Recent studies by the authors and others have shown that enhancer of zeste homolog2 (EZH2), a key subunit of polycomb complex 2 (PRC2), plays . . .
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