Ezhip constrains polycomb repressive complex 2 activity in germ cells

HIGHLIGHTS

• who: Roberta Ragazzini from the Research University, Fontenay-aux-Roses, France have published the article: EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors report the identification of a tissue-specific cofactor of PRC2, EZHIP. In human and mouse, the authors show that this cofactor is expressed primarily in gonads and that it limits PRC2-mediated H3K27me3 deposition. The authors focus on the Polycomb complex PRC2 to investigate this question.
• how: The authors evaluated sperm quality through computer-assisted images analysis of . . .
  

   

  

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