F110i and r278c troponin t mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers*

HIGHLIGHTS

• who: Olga M. Hernandez from the (UNIVERSITY) have published the research: F110I and R278C Troponin T Mutations That Cause Familial Hypertrophic Cardiomyopathy Affect Muscle Contraction in Transgenic Mice and Reconstituted Human Cardiac Fibers*, in the Journal: (JOURNAL) of July/25,/2005
• how: Generation of Transgenic Mice All animal studies were conducted in accordance with institutional guidelines.

SUMMARY

The clinical significance of an isolated report of a sudden death in a carrier of the R278C mutations may be questionable. In this report, the authors present studies on the physiological consequences of the . . .

 



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