Factor va is inactivated by activated protein c in the absence of cleavage sites at arg-306, arg-506, and arg-679*

HIGHLIGHTS

  • who: Marijn van der Neut Kolfschoten from the (UNIVERSITY) have published the research: Factor Va Is Inactivated by Activated Protein C in the Absence of Cleavage Sites at Arg-306, Arg-506, and Arg-679*, in the Journal: (JOURNAL) of October/27,/2003
  • what: The authors report on the mechanism of APC-catalyzed inactivation of rFVa-GQA. The aim of this study was to learn more about the mechanism underlying this unexpected observation.
  • how: Mutagenesis-In this study expression vectors (pMT2) were used containing the cDNA of FV in which two or three . . .

     

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