Faecalibacterium prausnitzii skews human dc to prime il10-producing t cells through tlr2/6/jnk signaling and il-10, il-27, cd39, and ido-1 induction

HIGHLIGHTS

• who: Frédéric Altare and Francine Jotereau from the Democritus University of Thrace, Greece have published the article: Faecalibacterium prausnitzii Skews Human DC to Prime IL10-Producing T Cells Through TLR2/6/JNK Signaling and IL-10, IL-27, CD39, and IDO-1 Induction, in the Journal: (JOURNAL)
• what: The authors show that a single F. prausnitzii encounter endowed DC with a unique array of properties that promote Tr1 Treg generation as well as decreased effector lymphocyte development.
• how: For blocking experiments the authors used rat neutralizing Ab to IL-10 (10 . . .
  

   

  

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