HIGHLIGHTS
- who: Joseph E. Friedlander and colleagues from the Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Medicine, Boston, MA, USA have published the research: Failure to Guard: Mitochondrial Protein Quality Control in Cancer, in the Journal: (JOURNAL)
- what: The authors discuss how alterations in components are linked to tumorigenesis whether they act as drivers suppressors or both.
SUMMARY
The remaining 13 transmembrane components of OXPHOS, which are encoded by mtDNA, are transcribed and translated in the mitochondrial_matrix, and then assembled and inserted into the IMM. To maintain proteostasis . . .
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