Fak downregulation suppresses stem-like properties and migration of human colorectal cancer cells

HIGHLIGHTS

  • who: Chunyan Xu and collaborators from the Department of Gastroenterology, Binzhou Medical University Hospital, Binzhou, Shandong, China have published the research: FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells, in the Journal: PLOS ONE of September/20,/2022
  • what: This study attempted to investigate that downregulation of FAK inhibits metastasis in colorectal cancer through the weakening of stem_cell-like properties and its mechanisms. This study shows that FAK inhibitor decreased the expression of p-AKT and of stemness-related proteins, such as Nanog, OCT4, CD133, CD44 and c-Myc, in . . .

     

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