HIGHLIGHTS
- who: GI cancer and collaborators from the Centre, Institute of Genetics and, University of, UK have published the article: FAK suppresses antigen processing and presentation to promote immune evasion in pancreatic cancer, in the Journal: (JOURNAL)
- what: The authors aimed to further investigate immunoregulatory function of focal adhesion kinase (FAK) in PDAC with specific emphasis on regulation of type-u00adII interferon response that is critical in promoting T-u00adcell tumour recognition and effective immunosurveillance. The authors show that FAK deletion in cancer cells derived from mouse KPC tumours reprogrammes the cellular response to IFNu03b3, increasing . . .
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