Farnesoid x receptor inhibits glucagon-like peptide-1 production by enteroendocrine l cells

HIGHLIGHTS

• who: burcelin from the Sahlgrenska University Hospital, Gothenburg, Sweden, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden. , Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne CH-1015, Switzerland. have published the research work: Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 27/03/2015
• what: The authors show that FXR activation in L cells decreases proglucagon expression by interfering with the glucose-responsive factor Carbohydrate-Responsive Element Binding Protein (ChREBP) and GLP . . .
  

   

  

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