Fas-associated phosphatase 1 (fap1) influences βcatenin activity in myeloid progenitor cells expressing the bcr-abl oncogene

HIGHLIGHTS

  • who: Weiqi Huang from the Oncomine, Research Addition, University of Michigan, Ann Arbor, MI have published the article: Fas-associated Phosphatase 1 (Fap1) Influences βCatenin Activity in Myeloid Progenitor Cells Expressing the Bcr-abl Oncogene, in the Journal: (JOURNAL) of October/20,/2012
  • what: The authors investigate the contribution of Fap1 to increased ␤catenin in Bcr-abl⫹ cells.
  • future: This will be the focus of future studies in the laboratory.

SUMMARY

    This interaction results in Fas dephosphorylation and inhibition of Fas-induced apoptosis. The human CML LSC is also . . .

     

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