HIGHLIGHTS
- who: Gael Galli et al. from the CNRS, ImmunoConcEpT, UMR, University Bordeaux, Bordeaux, France have published the paper: Fas/CD95 Signaling Pathway in Damage-Associated Molecular Pattern (DAMP)-Sensing Receptors, in the Journal: Cells 2022, 11, 1438. of /2022/
- what: The aim of this review is to question whether CD95 might act as an alarmin for Pattern Recognition Receptors (PRRs).
SUMMARY
Although most of the ALPS patients exhibit CD95 mutations, when Oliveira et_al revised the ALPS classification in 2010, lymphoproliferative disorders showing no mutations in CD95, CD95L, or caspase 10 were . . .
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