Fat loss in patients with metastatic clear cell renal cell carcinoma treated with immune checkpoint inhibitors

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SUMMARY

    Given that these changes, especially the rapid loss of adipose_tissue, are also reported to have prognostic value in cancer patients, and that ICI therapy can lead to substantial changes in body composition, it may be reasonable to assume that these changes are also associated with patient prognoses. The authors aimed to determine the prognostic impact of fat loss determined using cross-sectional imaging after ICI treatment in patients with metastatic ccRCC. The optimal cut-off and corresponding log-rank p values for ∆SF, ∆VF, and ∆TF were -5%/month and and amp;lt;0 . . .

     

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