HIGHLIGHTS
- who: Rebecca Harris et al. from the Rockefeller University Press JCell Biol. , Vol. , No. , e, have published the Article: Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells, in the Journal: (JOURNAL) of 12/01/2023
- what: The studies to identify the binding partners and substrates of Fbxo7 revealed an overlapping set of candidates that were identified as cyclin D3/Cdk6 substrates, including PFKP, the prominent PFK1 isoform expressed in T-ALL cells (Anders et_al, 2011; Stott et_al, 2019; Teixeira et_al, 2016). The authors show Fbxo7 expression is glucose-responsive at the . . .
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