HIGHLIGHTS
- who: Annie Qiu and collaborators from the United States University of Alabama at Birmingham have published the research: Fcu03b3RIV is required for IgG2c mediated enhancement of RBC alloimmunization, in the Journal: (JOURNAL)
- what: The authors show herein that FcgRIII-/- mice have normal induction of alloimmunization by IgG2c.
SUMMARY
There was discordance between RhD+ RBC clearance and immunoprophylaxis among the anti-D monoclonal_antibodies evaluated, challenging the explanation that anti-D works by clearing RhD + RBCs. To gain insight into how different subclasses modulate immune_responses, the authors previously reported the generation of monoclonal_antibodies . . .
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