HIGHLIGHTS
- who: Bruce D. Wines from the University of United States have published the paper: Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2, in the Journal: (JOURNAL)
- what: The authors report the development of multifunctional antiviral proteins by applying novel mutations of the Fc and glycan modification to manipulate the Fc component of ACE2-Fc which resulted variously in increased virus neutralization, complement directed killing and activation of FcgRIIIa. The authors examined different antiviral functions of ACE2-Fc virus decoy proteins.
- how: The activation of complement by the ACE2Fc proteins . . .
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