Fe-s cluster biogenesis in isolated mammalian mitochondria

HIGHLIGHTS

• who: Alok Pandey from the ‡Department of Pharmacology and Physiology, New Jersey Medical School, Rutgers University, Newark, New Jersey have published the article: Fe-S Cluster Biogenesis in Isolated Mammalian Mitochondria, in the Journal: (JOURNAL)
• what: Using cysteine as the source of sulfur here the authors show that mitochondria isolated from Cath.Aderived cells a murine neuronal cell line can synthesize and insert new Fe-35S clusters into aconitase and ferredoxins. Individual Requirements of GTP and for Cluster Assembly-The experiments described above were performed in one step and involved simultaneous import and Fe-S . . .
  

   

  

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