Fenfluramine: a review of pharmacology, clinical efficacy, and safety in epilepsy

HIGHLIGHTS

  • who: Debopam Samanta from the Child Neurology Section, Department of Pediatrics, University of Arkansas for Medical Sciences, Children's have published the research work: Fenfluramine: A Review of Pharmacology, Clinical Efficacy, and Safety in Epilepsy, in the Journal: Children 2022, 9, 1159. of /2022/
  • what: The analysis showed that 58-60% of patients never reached baseline seizure numbers over the entire trial period . The primary reason for discontinuation was lack of efficacy (22%).
  • future: Studies are needed to understand FFA's interaction with other commonly used ASMs such as lamotrigine rufinamide and topiramate . . .

     

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