HIGHLIGHTS
- who: Kai Xiao from the Department of Anesthesia, Wuhan Fourth Hospital, Hanzheng Street, Qiaokou District, Wuhan, Hubei, China have published the paper: Fentanyl activates ovarian cancer and alleviates chemotherapy-induced toxicity via opioid receptor-dependent activation of EGFR, in the Journal: (JOURNAL)
- what: The authors demonstrate that fentanyl enhances ovarian cancer cell biological functions and reverses chemotherapy-induced apoptosis through activation of EGFR, and furthermore that this is associated with opioid receptor. Using multiple cellular assays, the authors show that fentanyl at clinical concentrations promotes ovarian cancer growth and migration without affecting survival. The authors . . .
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