Ferritin triggers neutrophil extracellular trap-mediated cytokine storm through msr1 contributing to adult-onset still’s disease pathogenesis

HIGHLIGHTS

• who: Jinchao Jia from the Sigma-Aldrich, USA) was injected intraperitoneally (ip.) to WT FVB/n mice at a dose of , u03bcg/g of body weight. After treatment for, , and , h, mice were anesthetized with isoflurane inhalation for body weight measurement and blood collection, and then euthanized by, .5% chloral hydrate (0., mL/, g) and rapid cervical dislocation for liver and spleen collection. The size of liver and spleen were measured. The blood and serum were harvested for flow cytometry and cytokine analysis. Liver samples were collected, fixed in, % paraformaldehyde and embedded in paraffin. Additional liver samples . . .
  

   

  

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