Ferroptosis: a specific vulnerability of ras-driven cancers?

HIGHLIGHTS

  • who: Cristina Andreani from the Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, United States have published the research: Ferroptosis: A Specific Vulnerability of RAS-Driven Cancers?, in the Journal: (JOURNAL) of 15/07/2022
  • what: This is in line with the study showing that PLA2G4C, a cytosolic PLA2, is required to prevent ferroptosis in KMLC upon FASN inhibition . The aim of this perspective was to determine potential relationships between ferroptosis-related genes and RAS oncogenes across several cancer types. In the future, it will be of interest to compare DepMap . . .

     

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