Ferroptosis-related gene slc1a5 is a novel prognostic biomarker and correlates with immune microenvironment in hbv-related hcc

HIGHLIGHTS

  • who: Hanwen Su et al. from the Department of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan, China have published the research: Ferroptosis-Related Gene SLC1A5 Is a Novel Prognostic Biomarker and Correlates with Immune Microenvironment in HBV-Related HCC, in the Journal: (JOURNAL) of 10/02/2023
  • what: The authors demonstrated that SLC1A5, as an important modulator of ferroptosis, affects tumor immune microenvironment in HBV-related HCC via increasing the infiltrating Treg and macrophage cells, as well as up-regulating the levels of immune checkpoint-related genes (CTLA4, HAVCR2, LAG3 . . .

     

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