Ferroptosis: roles and molecular mechanisms in diabetic cardiomyopathy

HIGHLIGHTS

  • who: April et al. from the University of Missouri, United States have published the research work: Ferroptosis: roles and molecular mechanisms in diabetic cardiomyopathy, in the Journal: (JOURNAL)

SUMMARY

    Among them, 15.5% with type 1 diabetes_mellitus (T1DM) have abnormal myocardial systolic or diastolic function, whereas patients with type 2 diabetes_mellitus (T2DM) are mostly middle-aged and elderly, with a relatively higher risk of cardiovascular system complications. Genetically, ferroptosis is a biological process regulated by multiple genes, and a variety of genes involved in iron metabolism, lipid synthesis, and oxidative stress regulation can . . .

     

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