Fetal glucocorticoid receptor (nr3c1) deficiency alters the landscape of dna methylation of murine placenta in a sex-dependent manner and is associated to anxiety-like behavior in adulthood

HIGHLIGHTS

  • who: Michaela Schmidt from the (UNIVERSITY) have published the paper: Fetal glucocorticoid receptor (Nr3c1) deficiency alters the landscape of DNA methylation of murine placenta in a sex-dependent manner and is associated to anxiety-like behavior in adulthood, in the Journal: (JOURNAL)
  • what: The authors use a heterozygous Nr3c1 knockout mouse to determine the role of the fetal Nr3c1 gene in defining DNA methylation patterns and future behavior. The authors focused on fetal placenta since it is one of the few noninvasive sources of early life biological material at birth beside blood28,29 and perhaps . . .

     

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