HIGHLIGHTS
- who: August et al. from the University of Oregon, United States have published the research work: FGF-mediated establishment of left-right asymmetry requires Rab7 function in the dorsal mesoderm in, in the Journal: (JOURNAL)
- what: Using animal caps the authors show that Rab7 was required for both, FGF-dependent elongation and FGF-induced mesodermal identity, suggesting a general role of Rab7 in FGF/MAPK-dependent dorsal mesoderm specification in Xenopus. during later neurula stages in most vertebrates. With this approach the authors here demonstrated that Rab7 is required for correct LR asymmetry by regulating . . .
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