Fibroblast growth factor 2 inhibits myofibroblastic activation of valvular interstitial cells

HIGHLIGHTS

  • who: Marcus Ground and collaborators from the Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin have published the article: Fibroblast growth factor 2 inhibits myofibroblastic activation of valvular interstitial cells, in the Journal: PLOS ONE of February/10,/2022
  • what: The authors aimed to compare the observed changes in FGF-2 stimulated cells to TGF-u03b2 stimulated VICs, which can be thought of as a positive control for myofibroblastic activation. The study has used insulin as a mitotic agent in the FIB medium, and this addition may explain the findings here.
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