Figl1 and its novel partner flip form a conserved complex that regulates homologous recombination

HIGHLIGHTS

  • who: Joiselle Blanche Fernandes et al. from the Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium, VIB Center for Plant Systems (CNRS), Université Paris-Sud, CEA-Saclay, Gif-sur-Yvette, France have published the article: FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination, in the Journal: (JOURNAL)
  • what: The authors propose a model wherein FIGL1 and FLIP act as a complex that negatively regulates the strand invasion step of HR by interacting with DMC1/RAD51 and modulating their activity/dynamics.
  • how: The authors identified a novel protein complex . . .

     

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