Filament assembly underpins the double-stranded dna specificity of aim2-like receptors

HIGHLIGHTS

• who: Archit, Garg and Christina M., Stallings from the Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA have published the Article: Filament assembly underpins the double-stranded DNA specificity of AIM2-like receptors, in the Journal: (JOURNAL) of August/02,/2022
• what: Together, the experiments demonstrate that dsDNA provides the best signaling platform for AIM2 not only for initial assembly, but also for signal_transduction through ASC.
• how: Because dsDNA length is an important parameter . . .
  

   

  

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