Finasteride alleviates high fat associated protein-overload nephropathy by inhibiting trimethylamine n-oxide synthesis and regulating gut microbiota

HIGHLIGHTS

• who: d Protein-Overload and collaborators from the University of Mississippi Medical Center, United States have published the article: Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota, in the Journal: Gut Microbiota Analysis
• what: The authors demonstrated that HFD-induced hyperlipidemia exacerbated CKD progression characterized by the exacerbated kidney injury, deterioration of systematic inflammation, gut barrier disruption as well as intestinal microbiota dysfunction probably through elevation of serum TMAO level.
• how: Were analyzed with ImageJ software as previously described (Huante-Mendoza et_al 2016 . . .
  

   

  

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