Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the hla region

HIGHLIGHTS

  • who: Selene M. Clay from the Department of Human Genetics, University of Chicago, Chicago, IL, USA have published the paper: Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region, in the Journal: (JOURNAL) of July/19,/2017
  • what: The authors focused on significantly associated variants and amino_acid polymorphisms and applied a Bonferroni correction to the results from the heterogeneity test. Despite the delineation of specific HLA class I and class II variants and genes associated with risk for COA and AOA, the study had limitations.
  • how . . .

     

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