Five new polyoxypregnane glycosides from the vines of aspidopterys obcordata and their antinephrolithiasis activity

HIGHLIGHTS

  • who: Zhaocui Sun and collaborators from the College, Jinghong, China have published the article: Five New Polyoxypregnane Glycosides from the Vines of Aspidopterys obcordata and Their Antinephrolithiasis Activity, in the Journal: Molecules 2022, 4596 of /2022/
  • what: In this study, five new polyoxypregnane glycosides, obcordatas J-N , were obtained from 95% EtOH extracts of the dried vines of A. obcordata.
  • how: The results showed that compounds 1-3 have prominent protective effects on calcium oxalate crystal-induced human kidney 2 (HK-2) cells with EC50 values ranging from 6.72 to 14.00 . . .

     

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