Flash functional group-tolerant biaryl-synthesis based on integration of lithiation, zincation and negishi coupling in ow

HIGHLIGHTS

  • who: July and collaborators from the University of Adelaide, Australia have published the article: Flash functional group-tolerant biaryl-synthesis based on integration of lithiation, zincation and negishi coupling in ow, in the Journal: (JOURNAL)
  • what: The authors focused on the coupling process referred to as the Murahashi coupling (Murahashi et_al, 1979; Giannerini et_al, 2013) using aryl lithium as the aryl metal. The authors report the flow microsynthesis of functionalized biaryls by integrating lithiation, zincation, and coupling reactions mediated by functionalized aryl zinc.

SUMMARY

    A wide range of molecules have been . . .

     

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