Flexibility of in vitro cortical circuits influences resilience from microtrauma

HIGHLIGHTS

SUMMARY

    One such condition, traumatic brain injury (TBI), affects many of the levels of architecture intrinsic to the brain (Wolf and Koch, 2016; Kenzie et_al, 2017), and it can have longlasting sequelae potentially evolving into neurodegenerative disease (Hoskison et_al, 2009; Gupta and Sen, 2016; Hay et_al, 2016; Taylor et_al, 2017; Tagge et_al, 2018). Functional MRI studies in TBI patients report long-lasting altered connectivity, disconnection within the default mode network and impaired modular structure (Douw et_al, 2010; Caeyenberghs et_al, 2012, 2013, 2014; Pandit et_al, 2013; Han et_al, 2014; Power et_al, 2014; Fagerholm et_al, 2015), features . . .

     

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