Flotillins are involved in the polarization of primitive and mature hematopoietic cells

HIGHLIGHTS

  • who: Lawrence Rajendran et al. from the Systems and Cell of Neurodegeneration, Department of Psychiatry Research, University of Zurich, Zurich, Switzerland, Immunology, University of Konstanz have published the research: Flotillins Are Involved in the Polarization of Primitive and Mature Hematopoietic Cells, in the Journal: (JOURNAL) of December/22,/2009
  • what: Employing the membrane lipid-order sensitive probe Laurdan the authors show that flotillin accumulation in the immunological synapse is concomittant with membrane ordering in these regions. Based on the results the authors propose that in hematopoietic cells flotillins provide intrinsic cues that govern segregation of . . .

     

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