Fluorescent ligands for dopamine d2/d3 receptors

HIGHLIGHTS

  • who: Anni Allikalt from the Department have published the research: Fluorescent ligands for dopamine D2/D3 receptors, in the Journal: Scientific Reports Scientific Reports
  • what: For an initial set of fluorescent ligands, the authors focused on the incorporation of a dansyl label, a naphthalene-derived fluorophore emitting green light. For TIRF microscopy, the authors focused on the Cy3B-labeled ligand 10b, as the same fluorophore was previously used for the imaging of ­D2R and ­D3R14,17.
  • how: Data were analyzed with the one-site saturation binding model implemented in PRISM8.0 (GraphPad Software . . .

     

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