Fluorescent reporters and biosensors for probing the dynamic behavior of protein kinases

HIGHLIGHTS

  • who: Juan A. González-Vera and May C. Morris from the (UNIVERSITY) have published the research work: Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases, in the Journal: Proteomes 2015, 3, 369-410 of 17/07/2015
  • what: This approach has been widely implemented to study cell cycle regulated proteins ; for instance, to characterize the spatiotemporal shuttling of cyclins and cyclin-dependent kinases between the cytoplasm and the nucleus .

SUMMARY

    The conformation of active kinases differs from that of inactive kinases and protein_kinases undergo significant conformational . . .

     

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