Fluoxetine prevents aβ1-42-induced toxicity via a paracrine signaling mediated by transforming-growth-factor-β1

HIGHLIGHTS

• who: Filippo Caraci from the Department of Sciences, University of Catania, Catania, Italy, Istituto di Ricovero e Cura Carattere Scientifico Oasi have published the research: Fluoxetine Prevents Aβ1-42-induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1, in the Journal: (JOURNAL)
• what: The authors demonstrate that fluoxetine affected the conversion of Pro-TGF-β1 into active TGF-β1, likely through the activation of MMP-2. The authors identified a potential diseasemodifying activity of fluoxetine depending on a paracrine mechanism mediated by TGFβ1. The authors propose that stimulation of TGF . . .
  

   

  

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