HIGHLIGHTS
- who: Samuel Bell from the Cavendish Laboratory, University of Cambridge, Cambridge, United Kingdom have published the article: Focal Adhesion Kinase: The Reversible Molecular Mechanosensor, in the Journal: (JOURNAL)
- what: The authors develop a theoretical model describing the physical mechanism of a reversible single-molecule stiffness sensor. The authors focus all the discussion on the focal adhesion kinase, in association with integrin and talin, connecting the force-providing cytoskeletal F-actin and the varying-stiffness ECM.
SUMMARY
As the name suggests, FAK is abundant in the regions of focal adhesions, which are . . .
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